Mole Concept & Avogadro's Number Explained: Grams to Moles Conversion
Understand what a mole is in chemistry, learn Avogadro's number, and convert between grams and moles using molar mass for common elements and compounds.
Last updated: 2026-04-28
What Is a Mole?
The mole (symbol: mol) is the SI base unit for amount of substance. It is defined as exactly 6.02214076 × 10²³ elementary entities (atoms, molecules, ions, electrons, etc.). This number is called Avogadro's number (NA).
The mole bridges the atomic world and the everyday world: atoms are far too small to count individually, but a mole of them has a measurable mass in grams. Specifically, 1 mole of any element has a mass in grams equal to its atomic mass in atomic mass units (u or Da).
Grams to Moles Formula
moles = mass (g) ÷ molar mass (g/mol)
To go the other way: mass (g) = moles × molar mass (g/mol)
The molar mass of a compound is found by summing the atomic masses of all atoms in one formula unit, taken from the periodic table.
Molar Masses of Common Substances
| Substance | Formula | Molar Mass (g/mol) | Atoms/Molecules per Mole |
|---|---|---|---|
| Hydrogen gas | H2 | 2.016 | 6.022 × 10²³ |
| Water | H2O | 18.015 | 6.022 × 10²³ |
| Oxygen gas | O2 | 32.000 | 6.022 × 10²³ |
| Carbon dioxide | CO2 | 44.010 | 6.022 × 10²³ |
| Sodium chloride (table salt) | NaCl | 58.443 | 6.022 × 10²³ |
| Ethanol | C2H5OH | 46.068 | 6.022 × 10²³ |
| Glucose | C6H12O6 | 180.156 | 6.022 × 10²³ |
| Calcium carbonate | CaCO3 | 100.087 | 6.022 × 10²³ |
| Sulfuric acid | H2SO4 | 98.079 | 6.022 × 10²³ |
| Ammonia | NH3 | 17.031 | 6.022 × 10²³ |
Worked Examples: How Many Moles in 100 g?
The table below applies the formula moles = 100 g ÷ molar mass to show how moles relate to an identical mass of different substances.
| Substance | Molar Mass (g/mol) | Moles in 100 g | Molecules in 100 g |
|---|---|---|---|
| Water (H2O) | 18.015 | 5.551 | 3.343 × 10²&sup4; |
| Oxygen gas (O2) | 32.000 | 3.125 | 1.882 × 10²&sup4; |
| Carbon dioxide (CO2) | 44.010 | 2.272 | 1.369 × 10²&sup4; |
| Table salt (NaCl) | 58.443 | 1.711 | 1.031 × 10²&sup4; |
| Glucose (C6H12O6) | 180.156 | 0.555 | 3.343 × 10²³ |
Why Avogadro's Number Is What It Is
Avogadro's number was chosen so that 1 mole of carbon-12 atoms has a mass of exactly 12 grams. This definition tied the mole to the atomic mass unit (1 u = 1/12 the mass of a carbon-12 atom). Since 2019, the mole has been redefined by fixing NA = 6.02214076 × 10²³ mol−¹ exactly, independent of any physical artifact.
Concentration and Molarity
In solution chemistry, concentration is expressed as molarity (M) = moles of solute per liter of solution. A 1 M NaCl solution contains 58.443 g of NaCl dissolved in enough water to make 1 liter. Molarity connects the mole to laboratory measurement and is foundational to stoichiometry, titration, and reaction yield calculations.
Use our weight converter to convert between grams, milligrams, and other mass units when working through mole calculations.